All About Oxygen

• Introduction

• What is the Oxygen Cascade?

• How much oxygen is in the blood?

• How much oxygen is delivered to the tissues per minute?

• How much oxygen is extracted per minute?

• What is the oxyhemoglobin dissociation curve and why is it important?

• What problems are associated with right to left shunting?

• What is hypoxic pulmonary vasoconstriction?

• What are the effects of diffusion defects and ventilation-perfusion mismatches on arterial oxygenation?

• What is “absorption atelectasis”?

• What is pathological supply dependence on oxygen?

• How much oxygen do I give?

• How do I administer Oxygen?

• What is Hyperbaric Oxygen therapy?

• What is Carbon Monoxide Poisoning?

• Why is Oxygen considered toxic?

• How do Pulse Oximeters work?

• Clinical Scenario 1

• Clinical Scenario 2

• Clinical Scenario 3

• Clinical Scenario 4

• Key Points

• References

This section by Patrick Neligan MD (University of Pennsylvania).