Hyposphatemia Treatment

     
       

 

          
        There are a variety of different formulations of phosphate available, both in enteral and parenteral form. The route of administration depends on the speed and availability of that route. Of the parenteral formulations, both sodium and potassium phosphate are available. I usually use the potassium preparation, as most ICU patients are deficient in both potassium and phosphate. In addition, I almost always add KPO4 to the dialysis fluid in CVVHDF. If the patient is severely hypophosphatemic, then intravenous replenishment at 6mg/kg/hour is administered until the PO4 level is above 2mg/dl.
 

Table 3 Preparations available for Phosphate repletion

Preparation

Phosphate Content

Sodium

Potassium

Oral preparations

 

 

 

  Skim cow's milk

1 g/L

28 meq/L

38 meq/L

  Neutra-Phos

250 mg/packet

7.1 meq/packet

7.1 meq/packet

  Phospho-Soda

150 mg/mL

4.8 meq/mL

0

  Neutra-Phos K

250 mg/capsule

0

14.25 meq/capsule

  K-Phos Original

150 mg/capsule

0

3.65 meq/capsule

  K-Phos Neutral

250 mg/tablet

13 meq/tablet

1.1 meq/tablet

Intravenous preparations

 

 

 

  Neutral sodium potassium PO4

1.1 mmol/mL

0.2 meq/mL

0.02 meq/mL

  Neutral sodium PO4

0.09 mmol/mL

0.2 meq/mL

0

  Sodium PO4

3.0 mmol/mL

4.0 meq/mL

0

  Potassium PO4

3.0 mmol/mL

0

4.4 meq/mL
         
                   
       

         
     

       
       

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