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Phosphate is
involved in virtually every intracellular reaction, it is the body’s
source of chemical energy.
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Every metabolic action in the
body requires chemical energy – adenosine triphosphate (ATP). The high
energy bonds in ATP are derived from phosphate. This is essential for
muscle contractility, neuronal transmission and electrolyte transport.
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Phosphate is a key building
block for many essential intracellular compounds – nucleic acids,
phospholipids, enzymes, nucleoproteins.
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Many of the intracellular
messenger chemicals employ phosphate – cyclic AMP, cyclic GMP etc.
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It has an essential role in
both aerobic and anerobic metabolism, and in 2,3-DPG which is involved
with hemoglobin-oxygen interactions at tissue level.
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Phosphate is the main source of
intracellular buffer in the body, and is particularly important for
buffering volatile acid (CO2).
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Phosphate is involved in
cascades within the coagulation and immune systems.
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