TREATING SEPSIS

An 62 year old male presents with abdominal pain, hypotension, tachycardia, tachypnea, hypothermia and neutropenia. Presumed diagnosis – perforated diverticulum and fecal peritonitis.

This patient requires surgical source control and antibiotics. The most likely infecting organisms are Enterobacteriaceae, enteococci, S. pneumoniae and anaerobes. Broad spectrum treatment is required, without cover for pseudomonas.

Penicllin+beta Lactam inhibitor or ampicillin+aminoglycoside+anti-anaerobic agent

Ampicillin+Sulbactam or Piperacillin+Tazobactam or ampicillin+ gentamycin/aztreonam +metronidazole or imipenem

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